![]() 1 However, the natural history, clinical course, and long-term consequences of this new disease are still not completely understood. Although the consensus definition is likely to change as knowledge increases, this common framework provides a foundation for ongoing and future studies of epidemiology, risk factors, clinical characteristics, and therapy.Īs of Dec 3, 2021, more than 263 million confirmed cases of COVID-19 and more than 5♲ million deaths have been reported to WHO, although estimates of 2020 greatly surpass these figures. A separate definition might be applicable for children. Symptoms might also fluctuate or relapse over time. Symptoms might be new onset following initial recovery from an acute COVID-19 episode or persist from the initial illness. ![]() Common symptoms include, but are not limited to, fatigue, shortness of breath, and cognitive dysfunction, and generally have an impact on everyday functioning. 14 domains and 45 items were evaluated in two rounds of the Delphi process to create a final consensus definition for adults: post-COVID-19 condition occurs in individuals with a history of probable or confirmed SARS-CoV-2 infection, usually 3 months from the onset, with symptoms that last for at least 2 months and cannot be explained by an alternative diagnosis. In a WHO-led Delphi process, we engaged with an international panel of 265 patients, clinicians, researchers, and WHO staff to develop a consensus definition for this condition. The absence of a globally standardised and agreed-upon definition hampers progress in characterisation of its epidemiology and the development of candidate treatments. Known by a variety of names, including long COVID or long-haul COVID, and listed in the ICD-10 classification as post-COVID-19 condition since September, 2020, this occurrence is variable in its expression and its impact. ![]() People with COVID-19 might have sustained postinfection sequelae. ![]()
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